São Tomé and Príncipe competed at the 2020 Summer Olympics in Tokyo. Originally scheduled to take place from 24 July to 9 August 2020, the Games have been postponed to 23 July to 8 August 2021, because of the COVID-19 pandemic. It was the nation's seventh consecutive appearance at the Summer Olympics.
Competitors
The following is the list of number of competitors in the Games.
Athletics
São Tomé and Príncipe received a universality slot from the World Athletics to send a female track and field athlete to the Olympics.
- Track & road events
Canoeing
Sprint
São Tomé and Príncipe qualified a single boat (men's C-2 1000 m) for the Games by winning the gold medal at the 2019 African Games in Rabat, Morocco.
Qualification Legend: FA = Qualify to final (medal); FB = Qualify to final B (non-medal)
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